In Vitro Fertilisation cost in Turkey

How much does in vitro fertilisation cost in Turkey?

The average cost of in vitro fertilisation in Turkey in Istanbul is £2050. Depending on the needs, in vitro fertilisation costs from £1750 to £2350 in Turkey.

What is in vitro fertilisation?

Employing this technique, oocytes previously extracted with sperm are fertilized in the laboratory to generate embryos that can be transferred to the uterus or cryopreserved once developed.

In Vitro Fertilisation (IVF) in Turkey is an assisted human reproduction technique in which the woman’s oocytes are obtained from the ovaries previously stimulated with hormone treatment and fertilized in the laboratory with spermatozoa from the male partner to generate embryos which, once they have developed correctly, can be transferred to the patient’s uterus or cryopreserved.IVF

IVF is indicated in the following cases:

• Tubal factor (blocked fallopian tubes).
• infertility of unknown origin
• Failure of previous inseminations: infertility of unknown cause.
• Severe male factor: seminogram alterations.
• Genetic alteration necessitating preimplantation genetic diagnosis
• Some severe cases of polymicrocystic ovaries.

Stages of In Vitro Fertilisation (IVF)

1 – Ovulation stimulation in Istanbul

The woman undergoes hormonal stimulation of the ovaries to achieve oocyte maturation. There are different ovulation stimulation protocols that must be indicated depending on the cause of infertility, the hormonal profile and the age of the patient. The dosage of the drugs is also adjusted to the individual patient’s profile.

Treatment is most often in the form of injections that are administered subcutaneously by the patient herself. It is important to have a good number of oocytes available, as not all of them will fertilise and produce a good number of good quality embryos.

During the ovulation stimulation process, ultrasound and analytical controls are carried out to monitor the cycle to ensure a good response in terms of the quantity and quality of oocytes that we are going to obtain. This stage usually lasts a maximum of 15 days.

Ovulation stimulation medication has no significant side effects for the patient. However, there may be a feeling of fluid retention and/or slight abdominal discomfort. In terms of risks to be taken into account, ovarian hyperstimulation should be considered.

2 – Ultrasound-guided ovarian puncture

Once the oocytes have matured in the ovaries, they must be extracted so that they can be fertilised in the laboratory. It is performed under sedation and is therefore completely painless.

The follicular puncture usually lasts approximately 20 minutes. It is carried out in a surgical area, with the collaboration of the gynaecologist who performs the procedure, an anaesthetist, a nurse and the biologists who will collect the oocytes.

The oocytes are aspirated from the ovaries and transported to the laboratory in their own follicular fluid.

After the puncture, the patient will spend some time recovering from the anaesthesia and can then go home, where she will be advised to rest for the rest of the day.

3 – Fertilisation in the laboratory

Once the oocytes are in the laboratory, the sperm sample provided by the male partner or the sperm bank sample if a donor is used is processed.

There are two forms of fertilisation in Turkey

• Classic insemination consists of depositing a determined number of spermatozoa next to each egg and spontaneously producing fertilization.
• Insemination with sperm microinjection (ICSI), indicated in those cases of male cause or female factors that make us doubt about fertilization. ICSI consists of injecting sperm directly into the egg cell. Previously, the oocyte is “stripped” of the granulosa cells that accompany it to facilitate the microinjection and a morphologically normal sperm is selected to be microinjected.

In cases where the couple is vasectomized or the semen sample must be obtained by testicular biopsy (TESE), this is carried out simultaneously with the collection of oocytes to be taken to the laboratory for fertilization.

After fertilisation, the embryos are monitored in the laboratory. They are supervised by biologists and monitored to ensure their correct development in the initial stages. They are kept in incubators, at a constant temperature, in culture media suitable for their correct evolution.

Two to three days later, they are evaluated and selected for transfer to the patient and/or vitrification. Not all of them develop correctly, so some will interrupt their development and will be discarded for transfer.

In some cases, for different reasons, it is considered indicated to extend the culture of the embryos until a more advanced stage of development, called “Blastocyst” and will be transferred on the 5th or 6th day of development.

4- Embryo transfer in Turkey

The patient, who since the day of the follicular puncture has been treated with progesterone to favour the implantation capacity of the embryo in the uterus, goes to the reproduction centre where one or two embryos will be placed in the uterus.

The transfer technique is very simple in Turkey. It is carried out without anaesthesia because it is painless and under ultrasound control (ultrasound via the abdomen). A fine catheter is placed through the vagina which deposits the embryos in a specific place in the uterus where implantation is ideal.

After the transfer, the biologists proceed to vitrify the remaining embryos. The patient rests for a period of time in the clinic and is then transferred to her home, where she is advised to rest for the rest of the day.

In the days that follow and until the pregnancy test, which is carried out 13 days later, it is advisable not to do any intense physical exercise. For the pregnancy test, all you have to do is go to the centre on the appointed day for a β-HCG blood test and a few hours later you will be informed of the result.